BACTERIAL AND SENSITIVITY PATTERN OF PATHOGENS CAUSING VENTILATOR-ASSOCIATED PNEUMONIA IN INTENSIVE CARE UNIT

Highlight:1. Antimicrobial resistance bacteria isolated from VAP patients are often associated with high mortality and length of hospital stay. 2. Mortality in was 33.3% the group had a longer stay compared to non-VAP group. 3. The three most predominant that were found A. baumannii, P. aeruginosa, K. pneumoniae. Cefoperazone-sulbactam, meropenem amikacin more than 70% sensitive against these bacteria.Abstract:Background: Ventilator-Associated Pneumonia (VAP) is common nosocomial infection Intensive Care Unit (ICU). resistant Objective: This study aimed analyze pattern sensitivity among pathogens caused ICU. Materials Methods: conducted retrospectively by extracting data bacterial isolates sputum specimens Laboratory Clinical Microbiology, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia confirming clinical on suffering ICU ward. started January until December 2017. Results: total 148 isolated, 18 them diagnosed as VAP, 130 not VAP. Acinetobacter baumannii many 38 (9%) followed Pseudomonas aeruginosa 22 (2%), E. coli 16 (7%), Klebsiella pneumoniae 11 (1%). showed rate above cefoperazone-sulbactam (SCF), (MEM) (AK). Conclusion: cefoperazone-sulbactam, meropenem, amikacin.